Isolation of antioxidant components from Corni fructus

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Inhibitory effects of corni fructus extract on angiogenesis and adipogenesis.

Natural products in Chonnam, Korea were screened via anti-angiogenesis experiments, and 1 candidate product was identified, Corni fructus, which exerted dose-dependent inhibitory effects against angiogenesis, adipogenesis, and cell adhesion. C. fructus extract (CFE) exhibits an angiogenesis inhibitory effect superior to that of the EGCG from green tea leaves. The expression level of angiogenesi...

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Protective effects of morroniside isolated from Corni Fructus against renal damage in streptozotocin-induced diabetic rats.

In our previous study, we reported the renoprotective effect of Hachimi-jio-gan, a Chinese traditional prescription consisting of eight medicinal plants, and also reported the effect of Corni Fructus (Cornus officinalis SIEB. et ZUCC.), a component of Hachimi-jio-gan, on diabetic nephropathy using diabetic rats. In this study, we investigated the effects of morroniside isolated from Corni Fruct...

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Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging

We investigated the inhibition of advanced glycation endproduct (AGE) activity using the fluorescence characteristics of fractions and compounds from Corni Fructus. Corni Fructus extract and its iridoid glycoside components showed low inhibitory activities as well as the AGE inhibitor aminoguanidine. However, a low molecular weight polyphenol, 7-O-galloyl-D-sedoheptulose, and an antioxidant, tr...

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Antioxidative Action of Corni Fructus Aqueous Extract on Kidneys of Diabetic Mice

This study investigated the antioxidative action of Corni Fructus aqueous extract on kidneys of diabetic mice. The electron donating abilities of Corni Fructus aqueous extract and its antioxidant activities (XO, SOD, CAT, GST, eNOS) in kidneys of C57BL/6 or db/db mice were evaluated. For in vivo study, seven week-old male mice were divided into normal control group (NC, C57BL/6 mice) , diabetic...

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Antidiabetic Effects of Corni Fructus Extract in Streptozotocin-Induced Diabetic Rats

PURPOSE Diabetes is the leading cause of end-stage renal failure. The present study was undertaken to characterize the effects of Corni Fructus on diabetic nephropathy in streptozotocin-induced diabetic rats and their mechanisms. MATERIALS AND METHODS Streptozotocin-diabetic rats were orally administrated with Corni Fructus at a dose of 100, 200 or 400 mg/kg body mass for 40 days. RESULTS C...

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ژورنال

عنوان ژورنال: Korean Journal of Food Preservation

سال: 2020

ISSN: 1738-7248,2287-7428

DOI: 10.11002/kjfp.2020.27.2.204